Research Profile: Dr Ian Seppelt
Dr Ian SeppeltMB BS, BSc(Med), FANZCA, FJFICM
Contact Details:
Department of Intensive Care Medicine
Nepean Hospital (North Block)
University of Sydney
PO Box 63
Penrith NSW 2751
T: +61-2-47342000
F: +61-2-47343134
Email: Seppeli@wahs.nsw.gov.au
Positions Held:
Senior Staff Specialist in Intensive Care Medicine
Clinical Lecturer, Department of Medicine, University of Sydney
Research Interests:
Sedation and delirium in ICU. Projects include an RCT of a 'daily wakeup' protocol in ICU (the AROUSE study) and ongoing evaluations of the role of inhaled volatile anaesthetics for sedation in the ICU. Dr Seppelt is a member of a national Sedation and Agitation Advisory Board for intensive care.
Management of traumatic brain injury. Dr Seppelt is a member of the Management Committee for DECRA, a prospectice randomised controlled trial of early decompressive craniectomy in severe traumatic brain injury. Other inhouse studies include a prospective evaluation of the utility of brain oximetry in TBI using the LICOX and a clinical study of TBI metabolites and cytokines using microdialysis in 2006
Quality and safety. Ongoing prospective evaluations of adverse events of intrahospital transport of intensive care patients and the use of non invasive ventilation in intensive care. In 2006 Nepean will be participating in a multinational trial of two approaches to DVT prophylaxis in the ICU.
Management of shock in critical illness. Dr Seppelt was a principal investigator in the landmark SAFE trial (Saline versus Albumin Fluid Evaluation) and has ongoing interests in vasopressin and catecholamines in septic shock. He is national coordinator of the CRASH2 trial of tranexamic acid in traumatic haemorrhagic shock.